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10x Genomics
Chromium Single Cell ATAC

Glossary of Terms

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Duplicates: Two read pairs that originate from the same template molecule are called duplicates. Duplicates arise during the library preparation workflow when template molecules are amplified via PCR or linear amplification. Additionally, duplicate reads could also arise during the sequencing process and are generally referred to as optical duplicates. Duplicate reads provide redundant information and are identified computationally and collapsed into a single fragment record for downstream analysis.

Wavelet transform: A method to transform a one-dimensional signal (which can be thought of a time series) into a sum of linearly independent basis functions (wavelets) that are localized in time. It can be thought of as a generalization of the familiar Fourier transform that decomposes a time-varying signal into single-frequency sinusoidal waveforms.