10x Genomics Support/Single Cell ATAC/Documentation/Sequencing/

Cell Type Annotation Strategies for Single Cell ATAC-Seq Data

  • CG000234_TechnicalNote_CellTypeAnnotationUsingATAC_RevB.pdf

    Technical Note, CG000234

    CG000234_TechnicalNote_CellTypeAnnotationUsingATAC_RevB.pdf

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The starting point for interpretation of any single cell sequencing data is the annotation of cell clusters in a given dataset. Cell type annotation in single cell ATACseq data is challenging due to lack of specifically designed tools and use of unintuitive cis- and transregulatory elements in single cell ATAC-seq data. This Technical Note explores and demonstrates three different strategies that vary in the amount of bioinformatics expertise required for annotating cell types in single cell ATAC-seq data.

Document Type
Technical Note

Last Modified
March 30, 2022